Jornada 1
| 01 Ago 22 |  Real |
1 - 0 |  Lobos UPNFM |
7 |
| 31 Jul 22 |  CDyS Vida |
0 - 1 |  CD Olimpia |
7 |
| 31 Jul 22 |  Olancho FC |
1 - 1 |  Victoria |
6 |
| 31 Jul 22 |  Real |
0 - 2 |  Marathón |
2 |
| 01 Ago 22 |  FC Motagua |
4 - 0 |  Honduras |
4 |
Jornada 2
| 07 Ago 22 | Honduras |
0 - 2 | Marathón |
... |
| 08 Ago 22 | Real |
1 - 1 | FC Motagua |
11 |
| 07 Ago 22 | CDyS Vida |
1 - 0 | Olancho FC |
4 |
| 07 Ago 22 | Lobos UPNFM |
2 - 0 | Real |
... |
| 07 Ago 22 | CD Olimpia |
2 - 0 | Victoria |
2 |
Jornada 3
| 11 Ago 22 | Marathón |
1 - 2 | CD Olimpia |
40 |
| 10 Ago 22 | Real |
2 - 1 | Real |
22 |
| 11 Ago 22 | Victoria |
4 - 0 | Lobos UPNFM |
2 |
| 11 Ago 22 | Honduras |
2 - 2 | Olancho FC |
3 |
| 11 Ago 22 | FC Motagua |
2 - 2 | CDyS Vida |
24 |
Jornada 4
| 15 Ago 22 | Real |
2 - 1 | Victoria |
2 |
| 14 Ago 22 | CDyS Vida |
2 - 0 | Real |
3 |
| 14 Ago 22 | Lobos UPNFM |
1 - 2 | Honduras |
3 |
| 14 Ago 22 | Olancho FC |
0 - 1 | CD Olimpia |
13 |
| 15 Ago 22 | FC Motagua |
4 - 1 | Marathón |
4 |
Jornada 5
| 20 Ago 22 | Marathón |
4 - 4 | CDyS Vida |
12 |
| 22 Ago 22 | Victoria |
2 - 1 | Honduras |
8 |
| 21 Ago 22 | Lobos UPNFM |
2 - 3 | FC Motagua |
10 |
| 21 Ago 22 | Real |
1 - 2 | Olancho FC |
3 |
| 22 Ago 22 | CD Olimpia |
1 - 1 | Real |
10 |
Jornada 6
| 27 Ago 22 | Honduras |
0 - 1 | CDyS Vida |
22 |
| 29 Ago 22 | Real |
2 - 0 | Marathón |
8 |
| 28 Ago 22 | Victoria |
1 - 0 | Real |
... |
| 28 Ago 22 | Olancho FC |
0 - 1 | FC Motagua |
6 |
| 29 Ago 22 | CD Olimpia |
2 - 0 | Lobos UPNFM |
8 |
Jornada 7
| 01 Sep 22 | Marathón |
1 - 1 | Victoria |
8 |
| 01 Sep 22 | Lobos UPNFM |
1 - 2 | Olancho FC |
23 |
| 01 Sep 22 | Honduras |
4 - 0 | Real |
... |
| 01 Sep 22 | CDyS Vida |
1 - 0 | Real |
11 |
| 02 Sep 22 | FC Motagua |
1 - 0 | CD Olimpia |
36 |
Jornada 8
| 04 Sep 22 | Marathón |
1 - 1 | Lobos UPNFM |
7 |
| 04 Sep 22 | Victoria |
1 - 2 | CDyS Vida |
19 |
| 04 Sep 22 | Olancho FC |
3 - 1 | Real |
... |
| 04 Sep 22 | Real |
1 - 2 | FC Motagua |
2 |
| 05 Sep 22 | CD Olimpia |
1 - 1 | Honduras |
7 |
Jornada 9
| 12 Sep 22 | Real |
2 - 0 | Honduras |
5 |
| 11 Sep 22 | CDyS Vida |
2 - 1 | Lobos UPNFM |
13 |
| 11 Sep 22 | Olancho FC |
2 - 3 | Marathón |
9 |
| 11 Sep 22 | Real |
2 - 2 | CD Olimpia |
3 |
| 12 Sep 22 | FC Motagua |
2 - 1 | Victoria |
8 |
Jornada 10
| 19 Sep 22 | Honduras |
0 - 1 | FC Motagua |
5 |
| 18 Sep 22 | Marathón |
3 - 0 | Real |
3 |
| 18 Sep 22 | Victoria |
2 - 1 | Olancho FC |
12 |
| 19 Sep 22 | Lobos UPNFM |
2 - 2 | Real |
8 |
| 19 Sep 22 | CD Olimpia |
2 - 0 | CDyS Vida |
20 |
Jornada 11
| 01 Oct 22 | Marathón |
5 - 1 | Honduras |
... |
| 02 Oct 22 | Victoria |
0 - 2 | CD Olimpia |
7 |
| 02 Oct 22 | Olancho FC |
2 - 1 | CDyS Vida |
5 |
| 02 Oct 22 | Real |
0 - 2 | Lobos UPNFM |
1 |
| 02 Oct 22 | FC Motagua |
1 - 2 | Real |
12 |
Jornada 12
| 08 Oct 22 | Real |
1 - 3 | Real |
30 |
| 09 Oct 22 | CDyS Vida |
0 - 3 | FC Motagua |
14 |
| 09 Oct 22 | Lobos UPNFM |
2 - 2 | Victoria |
15 |
| 09 Oct 22 | Olancho FC |
2 - 1 | Honduras |
5 |
| 09 Oct 22 | CD Olimpia |
1 - 0 | Marathón |
14 |
Jornada 13
| 16 Oct 22 | Honduras |
2 - 2 | Lobos UPNFM |
15 |
| 15 Oct 22 | Marathón |
2 - 2 | FC Motagua |
29 |
| 16 Oct 22 | Victoria |
1 - 4 | Real |
13 |
| 16 Oct 22 | Real |
0 - 0 | CDyS Vida |
1 |
| 17 Oct 22 | CD Olimpia |
0 - 1 | Olancho FC |
29 |
Jornada 14
| 20 Oct 22 | Olancho FC |
7 - 0 | Real |
6 |
| 20 Oct 22 | Real |
0 - 0 | CD Olimpia |
40 |
| 20 Oct 22 | Honduras |
2 - 2 | Victoria |
3 |
| 20 Oct 22 | CDyS Vida |
2 - 2 | Marathón |
17 |
| 21 Oct 22 | FC Motagua |
2 - 2 | Lobos UPNFM |
47 |
Jornada 15
| 23 Oct 22 | Marathón |
2 - 0 | Real |
... |
| 23 Oct 22 | CDyS Vida |
0 - 0 | Honduras |
18 |
| 24 Oct 22 | Lobos UPNFM |
0 - 0 | CD Olimpia |
11 |
| 24 Oct 22 | Real |
2 - 5 | Victoria |
9 |
| 24 Oct 22 | FC Motagua |
1 - 3 | Olancho FC |
18 |
Jornada 16
| 06 Nov 22 | Real |
2 - 1 | CDyS Vida |
48 |
| 06 Nov 22 | Victoria |
2 - 1 | Marathón |
15 |
| 06 Nov 22 | Olancho FC |
3 - 0 | Lobos UPNFM |
8 |
| 06 Nov 22 | Real |
2 - 2 | Honduras |
4 |
| 07 Nov 22 | CD Olimpia |
4 - 0 | FC Motagua |
72 |
Jornada 17
| 13 Nov 22 | Honduras |
1 - 2 | CD Olimpia |
36 |
| 13 Nov 22 | Real |
4 - 3 | Olancho FC |
27 |
| 13 Nov 22 | CDyS Vida |
0 - 1 | Victoria |
70 |
| 14 Nov 22 | Lobos UPNFM |
2 - 1 | Marathón |
24 |
| 13 Nov 22 | FC Motagua |
2 - 2 | Real |
27 |
Jornada 18
| 19 Nov 22 | Honduras |
0 - 0 | Real |
35 |
| 19 Nov 22 | Lobos UPNFM |
3 - 2 | CDyS Vida |
17 |
| 19 Nov 22 | Marathón |
4 - 0 | Olancho FC |
13 |
| 19 Nov 22 | CD Olimpia |
2 - 0 | Real |
19 |
| 19 Nov 22 | Victoria |
1 - 0 | FC Motagua |
21 |
